N'-Nitrosonornicotine

N'-Nitrosonornicotine is a tobacco-specific N-nitrosamine and carcinogen that has been found in unburned tobacco and cigarette smoke. It induces the formation of DNA adducts in isolated rat nasal mucosa and esophagus. N'-Nitrosonornicotine induces tumor formation in rat esophagus and nasal cavity, mouse lung, forestomach, and trachea, and hamster trachea and forebrain. Urinary levels of N'-nitrosonornicotine are positively correlated with the risk of esophageal cancer in smokers.Formal Name: 3-(1-nitroso-2-pyrrolidinyl)-pyridine. CAS Number: 80508-23-2. Synonyms: NNN. Molecular Formula: C9H11N3O. Formula Weight: 177.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: slightly soluble, Methanol: slightly soluble. SMILES: O=NN1C(C2=CN=CC=C2)CCC1. InChi Code: InChI=1S/C9H11N3O/c13-11-12-6-2-4-9(12)8-3-1-5-10-7-8/h1,3,5,7,9H,2,4,6H2. InChi Key: XKABJYQDMJTNGQ-UHFFFAOYSA-N. Origin: Synthetic.