MNI-caged-L-glutamate TFA

Description: MNI-caged-L-glutamate, a derivative of glutamate conjugated with a 4-methoxy-7-nitroindolinyl (MNI) photoprotective group, remains pharmacologically inactive at neuronal glutamate receptors at concentrations up to mM. Upon light exposure (300 - 380 nm excitation), it rapidly releases L-glutamate by cleaving the MNI group within submicroseconds. This characteristic enables the investigation of fast synaptic glutamate receptor mechanisms in situ. Target: Others. Smiles: C(C(O)=O)(F)(F)F.C(CC[C@@H](C(O)=O)N)(=O)N1C=2C(=C(OC)C=CC2N(=O)=O)CC1