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Description: MK-0941 free base is an orally active glucokinase activator with potent glucose-lowering activity, making it a potential therapeutic agent for type 2 diabetes. Target: Glucokinase. Smiles: O(C1=CC(C(NC=2C=CN(C)N2)=O)=CC(O[C@H](CO)C)=C1)C=3C=CC(S(CC)(=O)=O)=NC3. References: Eiki J, et al. Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs. Mol Pharmacol. 2011 Dec,80(6):1156-65.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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