Methylatropine (nitrate)

Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50 = 12008). It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50 value of 5.5 µg/kg. Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.Formal Name: (3-endo)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane, mononitrate. CAS Number: 52-88-0. Synonyms: Atropine methyl nitrate. Molecular Formula: C18H26NO3 . NO3. Formula Weight: 366.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: C[N+]1([C@H](CC[C@H]1C2)C[C@@H]2OC(C(C3=CC=CC=C3)CO)=O)C.O=[N]([O-])=O. InChi Code: InChI=1S/C18H26NO3.NO3/c1-19(2)14-8-9-15(19)11-16(10-14)22-18(21)17(12-20)13-6-4-3-5-7-13,2-1(3)4/h3-7,14-17,20H,8-12H2,1-2H3,/q+1,-1/t14-,15+,16+,17?,. InChi Key: NEDVJZNVOSNSHF-KUMOIWDRSA-N.