Meranzin

Meranzin is a coumarin that has been found in Murraya exotica and has diverse biological activities. It is cytotoxic to NSCLC-N6 and KB cancer cells (IC50s = 14.6 and 12.3 µg/ml, respectively). Meranzin (10 mg/kg) increases the latency to paw withdrawal in the hot plate test and reduces xylene-induced ear edema in mice. It decreases paw edema induced by carrageenan in rats when administered at the same dose.Formal Name: 8-[[(2S)-3,3-dimethyl-2-oxiranyl]methyl]-7-methoxy-2H-1-benzopyran-2-one. CAS Number: 23971-42-8. Molecular Formula: C15H16O4. Formula Weight: 260.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. SMILES: CC1(C)O[C@H]1CC2=C3OC(C=CC3=CC=C2OC)=O. InChi Code: InChI=1S/C15H16O4/c1-15(2)12(19-15)8-10-11(17-3)6-4-9-5-7-13(16)18-14(9)10/h4-7,12H,8H2,1-3H3/t12-/m0/s1. InChi Key: LSZONYLDFHGRDP-LBPRGKRZSA-N. Origin: Plant/Citrus maxima peel.