MB-05032

MB-05032 is an inhibitor of fructose-1,6-bisphosphatase (FBPase, IC50s = 16 and 61 nM for human and rat liver FBPase, respectively). It increases glucose utilization and enhances glucose-stimulated insulin release in MIN6 insulinoma cells when used at concentrations of 50, 100, and 200 µM.Formal Name: P-[5-[2-amino-5-(2-methylpropyl)-4-thiazolyl]-2-furanyl]-phosphonic acid. CAS Number: 261365-11-1. Molecular Formula: C11H15N2O4PS. Formula Weight: 302.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. SMILES: NC1=NC(C2=CC=C(P(O)(O)=O)O2)=C(CC(C)C)S1. InChi Code: InChI=1S/C11H15N2O4PS/c1-6(2)5-8-10(13-11(12)19-8)7-3-4-9(17-7)18(14,15)16/h3-4,6H,5H2,1-2H3,(H2,12,13)(H2,14,15,16). InChi Key: XJMYIJPPDSZOPN-UHFFFAOYSA-N.