LX2343

Item number	Size	Datasheet	Manual	SDS	Delivery time	Price
TGM-T4398-2mg	2 mg				7 - 10 business days*	30.00€
TGM-T4398-5mg	5 mg				7 - 10 business days*	46.00€
TGM-T4398-1mL	1 ml				7 - 10 business days*	50.00€
TGM-T4398-10mg	10 mg				7 - 10 business days*	72.00€
TGM-T4398-25mg	25 mg				7 - 10 business days*	131.00€
TGM-T4398-50mg	50 mg				7 - 10 business days*	227.00€
TGM-T4398-100mg	100 mg				7 - 10 business days*	338.00€
TGM-T4398-200mg	200 mg	-	-	-	7 - 10 business days*	470.00€

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Description: LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 µM and acts as a... more

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Product information "LX2343"

Description: LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 µM and acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 µM. Additionally, LX2343 stimulates autophagy, promoting Abeta clearance. Target: Beta-Secretase, Beta Amyloid, PI3K, Autophagy, BACE. Smiles: COc1ccc(Cl)cc1N(CC(=O)Nc1ccc2OCOc2c1)S(=O)(=O)c1ccccc1. References: Guo XD,etal.Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance.Acta Pharmacol Sin. 2016 Sep,37(10):1281-1297.

Supplier:	TargetMol
Supplier-Nr:	T4398

Properties

Application:	BACE1 inhibitor
MW:	474.91 D
Formula:	C22H19ClN2O6S

Database Information

CAS :	333745-53-2\| Matching products
KEGG ID :	K04521 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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