Lucideric acid A

Description: Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation. Target: p38 MAPK, MMP, JNK. Smiles: [H][C@@]1(CC(=O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@]1([H])C[C@@H]3O)[C@H](C)CCC(O)=O. References: Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNFalpha± induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK.Biochem Biophys Res Commun. 2011 Apr 29,408(1):18-24.