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An allosteric inhibitor of soluble adenylyl cyclase (IC50 = 50 = 11 µM), inhibits the activity of mitochondrial complex IV in wild-type but not sAC knockout MEFs at 50 µM, reduces ischemia and reperfusion-induced swelling of, and ATP content decreases in, rat liver mitochondria at 1.2 mg/kg. Formulation: A solid. InChI: InChI=1S/C12H13ClN4S/c13-10-6-11(16-12(14)15-10)17(8-3-4-8)7-9-2-1-5-18-9/h1-2,5-6,8H,3-4,7H2,(H2,14,15,16). InChIKey: PDWZXKSZLRVSEH-UHFFFAOYSA-N. SMILES: NC1=NC(Cl)=CC(N(CC2=CC=CS2)C3CC3)=N1
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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