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Coenzyme in the oxidative decarboxylation reactions of glucose metabolism and the citric acid cycle. Although it is an essential growth factor for various micro-organisms. a-Lipoic acid, is a naturally occuring coenzyme containing a disulfide that has been used to treat polyneuropathies and hepatic disorders. a-Lipoic acid is a potent inhibitor of NFKB activation and HIV-1 tat driven gene expression. Synonyms: (+/-)-1,2-Dithiolane-3-pentanoic Acid, (+/-)-1,2-Dithiolane-3-valeric Acid, (+/-)-Thioctic Acid, (RS)-alpha-Lipoic Acid, DL-Thioctic Acid, Liposan, Lipothion, NSC 628502, NSC 90788, Protogen A, Thioctsan, Tioctacid, CAS No: 1077-28-7, Molecular Formula: C8H14O2S2, Molecular Weight: 206.3, Appearance: Light yellow to yellow solid, Melting Point: 60-62°C, Identification: IR, Heavy Metals: <0.001%, Residue on Ignition: <0.1%, Loss on Drying: <0.2%, Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) , Storage: 4°C
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