Linopirdine
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and... more
Product information "Linopirdine"
Description: Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM, Kv7, KCNQ Channels) inhibitor (IC50: 2.4 µM). Linopirdine is a cognitive enhancer. It acts by stimulating release of acetylcholine and other neurotransmitters.Linopirdine is a putative cognition-enhancing drug that increases acetylcholine release in rat brain tissue. Target: TRP/TRPV Channel, Potassium Channel. Smiles: O=C1N(c2ccccc2C1(Cc1ccncc1)Cc1ccncc1)c1ccccc1. References: Schnee ME, et al. Selectivity of linopirdine (DuP 996), a neurotransmitter release enhancer, in blocking voltage-dependent and calcium-activated potassium currents in hippocampal neurons. J Pharmacol Exp Ther. 1998 Aug,286(2):709-17.
| Keywords: | DuP 996 |
| Supplier: | TargetMol |
| Supplier-Nr: | T15758 |
Properties
| Application: | Dementia therapeutic agent |
| MW: | 391.46 D |
| Formula: | C26H21N3O |
Database Information
| CAS : | 105431-72-9| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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