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Description: Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase).Liarozole dihydrochloride is an imidazole derivative, it is being investigated as a non-hormonal agent in prostate cancer and in the treatment of various other cancers and skin disorders. Target: Retinoid Receptor, P450. Smiles: Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1. References: Bryson HM, et al. Liarozole. Drugs Aging. 1996 Dec,9(6):478-84, discussion 485.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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