Leucettinib-92
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Potent inhibitor of DYRK1A (IC50=1.2nM), DYRK1B (IC50=1.8nM), DYRK3 (IC50=19.3nM) and CLK2... more
Product information "Leucettinib-92"
Potent inhibitor of DYRK1A (IC50=1.2nM), DYRK1B (IC50=1.8nM), DYRK3 (IC50=19.3nM) and CLK2 (IC50=0.6nM) [1]. Inhibits the phosphorylation of Tau at Thr212 and cyclin D1 at Thr286. Corrects cognitive deficits in animal models of Down syndrome. iso-Leucettinib-92 (Prod. No. AG-MR-C0050) is a kinase-inactive isomer and should be used as a negative control together with this compound.
| Keywords: | LCTB-92, (Z)-2-((Adamantan-1-yl)amino)-5-(benzo[d]thiazol-6-ylmethylene)-3,5-dihydro-4H-imidazol-4-one |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-MR-C0049 |
Properties
| Application: | CLK2/DYRK1 inhibitor |
| MW: | 378,5 D |
| Formula: | C21H22N4OS |
| Format: | Solid |
Database Information
| CAS : | 2732859-57-1| Matching products |
| KEGG ID : | K08823 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H319 |
| P Phrases: | P280, P305, P351, P338 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed