LEE011

Item number	Size	Delivery time	Price
SYN-1213-M001	1 mg	3 - 9 business days*	66.00€
SYN-1213-M005	5 mg	3 - 9 business days*	106.00€
SYN-1213-M010	10 mg	3 - 9 business days*	158.00€
SYN-1213-M050	50 mg	3 - 9 business days*	461.00€
SYN-1213-M100	100 mg	3 - 9 business days*	-

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Solid. Soluble in DMSO. Orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin... more

Close menu

Product information "LEE011"

Solid. Soluble in DMSO. Orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathways, with potential antineoplastic activity. Specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.

Keywords:	LEE-011, Ribociclib
Supplier:	SYNkinase
Supplier-Nr:	1213

Properties

Application:	CDK4/CDK6 inhibitor
MW:	434,5 D
Formula:	C23H30N8O
Purity:	>95%
Format:	Solid

Database Information

CAS :	1211441-98-3\| Matching products
KEGG ID :	K02089 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

View product citations for antibody 1213 on CiteAb

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "LEE011"

Write a review