LAS191859

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T27799-500ug	500 µg		-		7 - 10 business days*		394.00€
TGM-T27799-1mg	1 mg				7 - 10 business days*		693.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Description: LAS191859 is a CRTH2/DP2 antagonist with IC50 values of 7.6, 9.58, 14 and 15.5nM for... more

Close menu

Product information "LAS191859"

Description: LAS191859 is a CRTH2/DP2 antagonist with IC50 values of 7.6, 9.58, 14 and 15.5nM for recombinant guinea pig, human, rat and mouse CRTH2/DP2 receptors, respectively. LAS191859 has a residence time half-life of 21h at CRTh2 that translates into a long-lasting in vivo efficacy that is independent of plasma levels. Target: Others. Smiles: C(N(C(=O)C1CC1)CC)C2=C(N3C=4C(C(CC(O)=O)=C3)=CC=C(C)N4)C=CC(C(F)(F)F)=C2. References: Calbet M, Andrés M, Armengol C, Bravo M, Eichhorn P, López R, García-González V, Roberts R, Miralpeix M. Pharmacological characterization of CRTh2 antagonist LAS191859: Long receptor residence time translates into long-lasting in vivo efficacy. Pharmacol Res. 2016 Sep,111:208-216. doi: 10.1016/j.phrs.2016.06.014. Epub 2016 Jun 16. PubMed PMID: 27317944.

Keywords:	LAS-191859, LAS 191859
Supplier:	TargetMol
Supplier-Nr:	T27799

Properties

MW:	459.46 D
Formula:	C24H24F3N3O3

Database Information

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "LAS191859"

Write a review