L-Glutamine

L-Glutamine is a conditionally essential amino acid involved in many biochemical processes. It is synthesized in vivo by glutamate and ammonia. It serves as a substrate for glutamine synthetase in neurons for the biosynthesis of the major excitatory and inhibitory neurotransmitters glutamate and GABA. L-Glutamine decreases adhesion of sickle red blood cells (RBCs) to human umbilical vein endothelial cells (HUVECs) when incubated ex vivo with patient-derived autologous plasma either alone or with LPS. It has commonly been used in cell culture media. Formulations containing L-glutamine have been used in the treatment of sickle cell disease.Formal Name: L-glutamine. CAS Number: 56-85-9. Synonyms: L-Gln, (+)-Glutamine, (S)-2,5-Diamino-5-Oxopentanoic Acid, NSC 27421. Molecular Formula: C5H10N2O3. Formula Weight: 146.1. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Water: Slightly Soluble. SMILES: NC(CC[C@H](N)C(O)=O)=O. InChi Code: InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1. InChi Key: ZDXPYRJPNDTMRX-VKHMYHEASA-N.