Kinsenoside

Description: Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities. Kinsenoside could be useful for repairing beta cells in pancreatic islet injury as well as improving its function, it could promote the glucose tolerance of acute glucose increase in both diabetic and normal healthy rats. Kinsenoside inhibits osteoclastogenesis from macrophages by attenuating RANKL-induced NF-kappaB and NFATc1 activities, which in turn, prevents bone loss from OVX mice. Target: Apoptosis, Nrf2. Smiles: OC[C@H]1O[C@@H](O[C@H]2COC(=O)C2)[C@H](O)[C@@H](O)[C@@H]1O. References: Zhang Y , Cai J , Ruan H , et al. Antihyperglycemic activity of kinsenoside, a high yielding constituent from Anoectochilus roxburghii in streptozotocin diabetic rats[J]. Journal of Ethnopharmacology, 2007, 114(2):0-145.