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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T78054-5mg | 5 mg |
7 - 10 business days* |
671.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: JNJ-1013 is a potent and selective IRAK1 degrader, with IC50 values of 72 nM for... more
Product information "JNJ-1013"
Description: JNJ-1013 is a potent and selective IRAK1 degrader, with IC50 values of 72 nM for IRAK1, 443 nM for IRAK4, and 1071 nM for VHL FP. It induces apoptosis, increases cleaved PARP expression, and decreases the expression of IRAK1, p-IKBalpha, and pSTAT3(Tyr705) [1]. Target: Apoptosis. Smiles: C([C@@H](NC(COC1CCN(CC1)C2=CC(OC)=C(NC(=O)C=3N=C(C=CC3)C=4C=CNN4)C=C2)=O)C(C)(C)C)(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C=7SC=NC7C)=O)C[C@@H](O)C5
| Supplier: | TargetMol |
| Supplier-Nr: | T78054 |
Properties
| MW: | 878.05 D |
| Formula: | C46H55N9O7S |
Database Information
| CAS : | 2597343-08-1| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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