JCS-1

JCS-1
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T203316-10mg 10 mg -

7 - 10 business days*

-
TGM-T203316-50mg 50 mg -

7 - 10 business days*

-
 
Description: JCS-1 is a potent DcpSPROTAC degrader. It non-covalently binds to DcpS via an... more
Product information "JCS-1"
Description: JCS-1 is a potent DcpSPROTAC degrader. It non-covalently binds to DcpS via an RG3039-based warhead and recruits the E3 ligase VHL. JCS-1 facilitates the ubiquitination and degradation of DcpS at nanomolar concentrations, with a DC50 of 87 nM in MOLM-14 cells. This compound can be utilized in research on acute myeloid leukemia and other DcpS-dependent genetic disorders.
Supplier: TargetMol
Supplier-Nr: T203316

Properties

MW: 1174.41 D
Formula: C62H79N9O12S

Database Information

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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