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Description: ISO-1 (MIF Antagonist) is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-kappaB and TNF-alpha secretion from LPS-treated macrophages. Target: Others. Smiles: COC(=O)CC1CC(=NO1)c1ccc(O)cc1. References: Xu L, et al. Drug Discov Today. 2013 Jun,18(11-12):592-600.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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