Iptacopan hydrochloride
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly... more
Product information "Iptacopan hydrochloride"
Description: Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. Target: Complement System. Smiles: Cl.CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O. References: Dimitrios C Mastellos, et al. Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria. Semin Hematol. 2018 Jul,55(3):167-175.
| Keywords: | Iptacopan HCl, LNP023 hydrochloride |
| Supplier: | TargetMol |
| Supplier-Nr: | T9189 |
Properties
| Application: | CFB inhibitor |
| MW: | 458.98 D |
| Formula: | C25H31ClN2O4 |
Database Information
| CAS : | 1646321-63-2| Matching products |
| KEGG ID : | K01335 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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