These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Conversion and usertracking via Google Tag Manager
Product information "Indoxyl Sulfate (potassium salt)"
Indoxyl sulfate is a metabolite of tryptophan derived from dietary protein. Tryptophan is metabolized by intestinal bacteria into indole, which is absorbed into the blood and then further metabolized to indoxyl sulfate in the liver, which is normally excreted in urine. In chronic kidney disease patients where renal function is compromised, indoxyl sulfate can accumulate in serum as a uremic toxin, inducing oxidative stress and accelerating progression of the disease. Indoxyl sulfate at 250 µM can induce the activation of NF-kappaB, promoting the expression of both TGF-beta1 and Smad3 expression in proximal tubular cells of rats, which is associated with profibrotic activity.
3-(hydrogen sulfate), 1H-indol-3-ol, monopotassium salt