Indoxyl Sulfate (potassium salt)

Indoxyl Sulfate (potassium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16926-100 100 mg -

5 - 10 business days*

37.00€
Cay16926-250 250 mg -

5 - 10 business days*

68.00€
Cay16926-500 500 mg -

5 - 10 business days*

114.00€
Cay16926-1 1 g -

5 - 10 business days*

160.00€
 
Indoxyl sulfate is a metabolite of tryptophan derived from dietary protein. Tryptophan is... more
Product information "Indoxyl Sulfate (potassium salt)"
Indoxyl sulfate is a metabolite of tryptophan derived from dietary protein. Tryptophan is metabolized by intestinal bacteria into indole, which is absorbed into the blood and then further metabolized to indoxyl sulfate in the liver, which is normally excreted in urine. In chronic kidney disease patients where renal function is compromised, indoxyl sulfate can accumulate in serum as a uremic toxin, inducing oxidative stress and accelerating progression of the disease. Indoxyl sulfate at 250 µM can induce the activation of NF-kappaB, promoting the expression of both TGF-beta1 and Smad3 expression in proximal tubular cells of rats, which is associated with profibrotic activity.
Keywords: 3-(hydrogen sulfate), 1H-indol-3-ol, monopotassium salt
Supplier: Cayman Chemical
Supplier-Nr: 16926

Properties

Application: Tryptophan metabolite
MW: 251.3 D
Formula: C8H6NO4S . K
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 2642-37-7| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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