(±)-Indoxacarb

(±)-Indoxacarb is a broad-spectrum oxadiazine insecticide. It is metabolized in vivo to its active N-decarbomethoxyllated metabolite DCJW. Topical administration of (±)-indoxacarb is lethal to S. frugiperda, H. virescens, L. lineolaris, N. cincticeps, N. lugens, L. decemlineata, A. grandis, and M. domestica (LD50s = 0.03, 0.44, 1.6, 0.72, >7.8, 2.81, 6.45, and 15 ng/mg, respectively). It suppresses voltage-gated sodium channel currents in rat dorsal root ganglion neurons in a concentration-dependent manner. Formulations containing (±)-indoxacarb have been used to control various insect pests in tea farming.Formal Name: 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]-indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid, methyl ester. CAS Number: 144171-61-9. Synonyms: DPX-JW062, DPX-MP062. Molecular Formula: C22H17ClF3N3O7. Formula Weight: 527.8. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Ethanol: soluble*. lambdamax: 226, 285, 311 nm. SMILES: O=C(N(C1=CC=C(OC(F)(F)F)C=C1)C(OC)=O)N2N=C3C(CC4=C3C=CC(Cl)=C4)(C(OC)=O)OC2. InChi Code: InChI=1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3. InChi Key: VBCVPMMZEGZULK-UHFFFAOYSA-N.