Indirubin-3'-monoxime

Indirubin-3'-monoxime
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T5200-2mg 2 mg - - -

7 - 10 business days*

31.00€
TGM-T5200-200mg 200 mg - - -

7 - 10 business days*

536.00€
 
Description: Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3beta (IC50:... more
Product information "Indirubin-3'-monoxime"
Description: Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3beta (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/cyclin B, Cdk2/cyclin E). Target: Lipoxygenase, GSK-3, CDK. Smiles: ON=C1C(Nc2ccccc12)=C1C(=O)Nc2ccccc12. References: Leclerc S, et al. Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? J Biol Chem. 2001 Jan 5,276(1):251-60.
Keywords: Indirubin-3'-oxime
Supplier: TargetMol
Supplier-Nr: T5200

Properties

MW: 277.28 D
Formula: C16H11N3O2

Database Information

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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