Incensol acetate

Oil. Soluble in DMSO, dichloromethane or ethyl ether. Insoluble in water. Almost insoluble in ethanol or methanol. Component of the frankincense essential oil, Activator of transient receptor potential vanilloid 3 (TRPV3), a heat-sensitive ion channel involved in skin heat sensitivity, thermoregulation and neurological activities. Less powerful TRPV3 agonist than incensol (Prod. No. AG-CN2-0482), Shows in vivo neuroprotective properties. Causes anxiolytic-like and antidepressive-like behavioral effects in wild-type (WT) mice, Anti-inflammatory agent, Shown to have COX-1 and COX-2 inhibitory activity and cytotoxic activity against selected cancer cell lines.