Idoxuridine

Idoxuridine is a nucleoside analog that is used as an antiviral drug against herpes simplex virus type 1 keratitis. It is incorporated into viral DNA and blocks DNA replication. Idoxuridine shows poor selectivity for viral DNA.Formal Name: 2'-deoxy-5-iodo-uridine. CAS Number: 54-42-2. Synonyms: 5-iodo-2'-deoxyuridine, NSC 39661, SKF 14287. Molecular Formula: C9H11IN2O5. Formula Weight: 354.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 16 mg/mL, DMSO: 10 mg/mL, PBS (pH 7.2): 5 mg/mL. lambdamax: 215, 284 nm. SMILES: IC1=CN(C(NC1=O)=O)[C@H]2C[C@H](O)[C@@H](CO)O2. InChi Code: InChI=1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1. InChi Key: XQFRJNBWHJMXHO-RRKCRQDMSA-N.