Hypotaurine

Hypotaurine
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay29614-100 100 mg -

6 - 10 business days*

69.00€
Cay29614-250 250 mg -

6 - 10 business days*

161.00€
 
Hypotaurine is an endogenous inhibitory amino acid. It inhibits GABA uptake by mouse GABA... more
Product information "Hypotaurine"
Hypotaurine is an endogenous inhibitory amino acid. It inhibits GABA uptake by mouse GABA transporter 1 (GAT1), GAT2, GAT3, and GAT4 (IC50s = 170, 240, 4.9, and 8.1 µM, respectively) and rat GAT1, GAT2, and GAT3 (IC50s = 1,010, 52, and 73 µM, respectively). Hypotaurine also inhibits GABA uptake by betaine/GABA transporter 1 (BGT1) in L-M(TK-) cells expressing the human transporter (IC50 = 380 µM). It inhibits sodium-stimulated GABA uptake by rabbit choroid plexus slices (IC50 = 21.9 µM). It scavenges hypochlorous acid (HOCl) and hydroxyl, but not superoxide, radicals in cell-free assays. Hypotaurine (1 mM) protects rat TR-TBT 18d-1 placental trophoblasts from hydrogen peroxide-induced cell death.Formal Name: 2-amino-ethanesulfinic acid. CAS Number: 300-84-5. Molecular Formula: C2H7NO2S. Formula Weight: 109.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 10 mg/ml. SMILES: NCCS(O)=O. InChi Code: InChI=1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5). InChi Key: VVIUBCNYACGLLV-UHFFFAOYSA-N.
Keywords: 2-amino-ethanesulfinic acid
Supplier: Cayman Chemical
Supplier-Nr: 29614

Properties

Application: Endogenous inhibitory amino acid, GABA uptake inhibitor
MW: 109.1 D
Formula: C2H7NO2S
Purity: >95%
Format: Solid

Database Information

CAS : 300-84-5| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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