HY-17542

HY-17542 is an inhibitor of the severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro, IC50 = 2.6 µM). It increases the viability of SARS-CoV-infected Vero E6 cells (EC50 = 13.1 µM).Formal Name: 5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-benzamide. CAS Number: 1093070-14-4. Synonyms: PLpro Inhibitor 6. Molecular Formula: C22H22N2O2. Formula Weight: 346.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml. lambdamax: 224 nm. SMILES: O=C(C1=CC(NC(C)=O)=CC=C1C)N[C@@H](C2=CC=CC3=C2C=CC=C3)C. InChi Code: InChI=1S/C22H22N2O2/c1-14-11-12-18(24-16(3)25)13-21(14)22(26)23-15(2)19-10-6-8-17-7-4-5-9-20(17)19/h4-13,15H,1-3H3,(H,23,26)(H,24,25)/t15-/m1/s1. InChi Key: KGPYBLOBHQLIET-OAHLLOKOSA-N.