Hh-Ag1.5

Item number	Size	Delivery time	Price
TGM-T24754-1mg	1 mg	7 - 10 business days*	122.00€
TGM-T24754-5mg	5 mg	7 - 10 business days*	303.00€
TGM-T24754-1mL	1 ml	7 - 10 business days*	351.00€
TGM-T24754-10mg	10 mg	7 - 10 business days*	468.00€
TGM-T24754-25mg	25 mg	7 - 10 business days*	778.00€
TGM-T24754-50mg	50 mg	7 - 10 business days*	1,099.00€
TGM-T24754-100mg	100 mg	7 - 10 business days*	1,535.00€

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Description: Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened... more

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Product information "Hh-Ag1.5"

Description: Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quiescent state of non-injured hepatic stem cells and thus rescues liver failure. Hh-Ag1.5 induced differentiation of hiPSCs into skin precursor cells, spinal motor neurons and spinal sensory neurons. Target: Hedgehog/Smoothened. Smiles: CN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2c(F)ccc(F)c2c1Cl. References: King RW. Roughing up Smoothened: chemical modulators of hedgehog signaling. J Biol. 2002 Nov 6,1(2):8.

Keywords:	SAG-1.5, SAG1.5, SAG 1.5
Supplier:	TargetMol
Supplier-Nr:	T24754

Properties

MW:	526.04 D
Formula:	C28H26ClF2N3OS

Database Information

CAS :

612542-14-0| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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