HDAC1-IN-5

Item number	Size	Delivery time	Price
TGM-T61433-25mg	25 mg	7 - 10 business days*	1,440.00€
TGM-T61433-50mg	50 mg	7 - 10 business days*	1,877.00€
TGM-T61433-100mg	100 mg	7 - 10 business days*	2,371.00€

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Description: HDAC1-IN-5, a potent inhibitor of HDAC1 with an IC50 value of 15 nM, also exhibits... more

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Product information "HDAC1-IN-5"

Description: HDAC1-IN-5, a potent inhibitor of HDAC1 with an IC50 value of 15 nM, also exhibits inhibitory activity towards HDAC6 with an IC50 value of 20 nM. In cancer cells, HDAC1-IN-5 enhances the acetylation of both histone H3 and alpha-tubulin, leading to the activation of caspase 3 and induction of apoptosis. Additionally, HDAC1-IN-5 binds with DNA, causing chromatin damage. Furthermore, it demonstrated strong inhibitory activity against tumor growth in xenograft mice. [1]. Target: Others

Supplier:	TargetMol
Supplier-Nr:	T61433

Properties

MW:	367.46 D
Formula:	C20H21N3O2S

Database Information

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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