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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay19620-250 | 250 µg | - |
6 - 10 business days* |
93.00€
|
|||
| Cay19620-1 | 1 mg | - |
6 - 10 business days* |
321.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Harzianopyridone is an atpenin-like inhibitor of mammalian and nematode mitochondrial complex II... more
Product information "Harzianopyridone"
Harzianopyridone is an atpenin-like inhibitor of mammalian and nematode mitochondrial complex II (succinate:ubiquinone oxidoreductase, SQR) with IC50 values of 0.017, 0.2, and 2 µM for bovine, rat, and nematode complex II, respectively. It also inhibits nematode quinol-fumarate reductase (QFR, IC50 = 0.36 µM). Harzianopyridone is selective for complex II over complexes I and III in rats and cattle and complex I in nematodes (IC50s >100 µM). It has antibacterial and antifungal activity (EC50s = 35.9, 42.2, 60.4, and 50.2 µg/ml against R. solani, S. rolfsii, M. phaseolina, and F. oxysporum, respectively).Formal Name: 4-hydroxy-5,6-dimethoxy-3-[(2S,4E)-2-methyl-1-oxo-4-hexen-1-yl]-2(1H)-pyridinone. CAS Number: 137813-88-8. Synonyms: (-)-Harzianopyridone. Molecular Formula: C14H19NO5. Formula Weight: 281.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Soluble. SMILES: O=C1NC(OC)=C(OC)C(O)=C1C([C@@H](C)C/C=C/C)=O. InChi Code: InChI=1S/C14H19NO5/c1-5-6-7-8(2)10(16)9-11(17)12(19-3)14(20-4)15-13(9)18/h5-6,8H,7H2,1-4H3,(H2,15,17,18)/b6-5+/t8-/m0/s1. InChi Key: FPYAYFJAGDIMEX-GJIOHYHPSA-N. Origin: Fungus/Trichoderma harzianum sp. FKI-1509.
| Keywords: | (-)-Harzianopyridone, 4-hydroxy-5,6-dimethoxy-3-[(2S,4E)-2-methyl-1-oxo-4-hexen-1-yl]-2(1H)-pyridinone |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 19620 |
Properties
| Application: | Mitochondrial complex II (succinate:ubiquinone oxidoreductase) inhibitor, antibiotic |
| MW: | 281.3 D |
| Formula: | C14H19NO5 |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 137813-88-8| Matching products |
| KEGG ID : | K00235 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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