HA1077 (Fasudil, 1-(5-Isoquinolinesulfonyl)-1H-hexahydro-1,4-diazepine¥2HCl, 1-(5-Isoquinolinesulfon

The monohydrochloride salt is the form used to prepare formulations of this drug for clinical use. Note that the solubility properties of the mono- and di-HCl salts are different. Kinase inhibitor, has antivasospastic properties. Solubility: Very soluble in water, up to 200mg/ml or more, soluble in DMSO up to about 10mg/ml, not soluble in ethanol, addition of an aqueous solution of this dihydrochloride salt into a buffer solution may significantly alter its solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.