GS-441524 tris-isobutyryl ester

GS-441524 tris-isobutyryl ester
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T36440-500ug 500 µg -

7 - 10 business days*

250.00€
TGM-T36440-1mg 1 mg

7 - 10 business days*

448.00€
 
Description: GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog... more
Product information "GS-441524 tris-isobutyryl ester"
Description: GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with an EC50value of 0.26 µM. Target: Others. Smiles: CC(C)C(=O)OC[C@H]1O[C@@](C#N)([C@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)c1ccc2c(N)ncnn12. References: Mackman, R.L., Hui, H.C., Perron, M., et al.Prodrugs of a 1'-CN-4-aza-7,9-dideazaadenosine C-nucleoside leading to the discovery of remdesivir (GS-5734) as a potent inhibitor of respiratory syncytial virus with efficacy in the african green monkey model of RSVJ. Med. Chem.64(8)5001-5017(2021)
Supplier: TargetMol
Supplier-Nr: T36440

Properties

MW: 501.54 D
Formula: C24H31N5O7

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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