GPNA hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2(SLC1A5) inhibitor.... more
Product information "GPNA hydrochloride"
Description: GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2(SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme gamma-glutamyltransferase (GGT). GPNA hydrochloride also inhibits Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2. Target: Apoptosis, Others. Smiles: Cl.NC(=O)CCC(Nc1ccc(cc1)[N+]([O-])=O)C(O)=O. References: Corti A, et al. gamma-Glutamyltransferase enzyme activity of cancer cells modulates L-gamma-glutamyl-p-nitroanilide (GPNA) cytotoxicity. Sci Rep. 2019 Jan 29,9(1):891.
| Supplier: | TargetMol |
| Supplier-Nr: | T15411 |
Properties
| MW: | 303.7 D |
| Formula: | C11H14ClN3O5 |
Database Information
| CAS : | 67953-08-6| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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