GO289
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
GO289 is an inhibitor of casein kinase 2 (CK2, IC50 = 7 nM). It is selective for CK2 over a panel... more
Product information "GO289"
GO289 is an inhibitor of casein kinase 2 (CK2, IC50 = 7 nM). It is selective for CK2 over a panel of 59 other kinases at 5 µM. GO289 (8 or 24 µM) increases the circadian period in a reporter assay using U2OS cells. It decreases levels of phosphorylated Akt and cell division cycle 37 (Cdc37) in C2C12 skeletal muscle myoblasts when used at concentrations of 1, 2, 3, or 4 µM. InChI: InChI=1S/C17H15BrN4O2S/c1-24-15-8-12(13(18)9-14(15)23)10-19-22-16(20-21-17(22)25-2)11-6-4-3-5-7-11/h3-10,23H,1-2H3 InChIKey: DARDDBZKGVEVKB-UHFFFAOYSA-N SMILES: CSC1=NN=C(C2=CC=CC=C2)N1N=CC3=C(Br)C=C(O)C(OC)=C3
| Keywords: | 5-bromo-2-methoxy-4-[[[3-(methylthio)-5-phenyl-4H-1,2,4-triazol-4-yl]imino]methyl]-phenol |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43959 |
Properties
| Application: | CK2 inhibitor |
| MW: | 419.3 D |
| Formula: | C17H15BrN4O2S |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 694522-87-7| Matching products |
| KEGG ID : | K03097 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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