GLPG1205

Item number	Size	Manual	SDS	Delivery time	Price
Cay33185-1	1 mg	-	-	5 - 10 business days*	101.00€
Cay33185-5	5 mg	-	-	5 - 10 business days*	398.00€
Cay33185-10	10 mg	-	-	5 - 10 business days*	647.00€

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A GPR84 antagonist, inhibits DIM-induced GTPgammaS binding in cells overexpressing human GPR84... more

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Product information "GLPG1205"

A GPR84 antagonist, inhibits DIM-induced GTPgammaS binding in cells overexpressing human GPR84 (IC50 = 54 nM), inhibits embelin-induced chemotaxis of isolated human neutrophils (IC50 = 11 nM), reduces body weight loss and rectal bleeding and improves stool consistency in a rat model of DSS-induced colitis. Formulation: A solid. InChI: InChI=1S/C22H22N2O4/c25-22-23-21(28-14-18-13-26-9-10-27-18)12-20-19-6-5-16(4-3-15-1-2-15)11-17(19)7-8-24(20)22/h5-6,11-12,15,18H,1-2,7-10,13-14H2/t18-/m0/s1. InChIKey: IRBAWVGZNJIROV-SFHVURJKSA-N. SMILES: O=C1N2C(C3=CC=C(C#CC4CC4)C=C3CC2)=CC(OC[C@@H]5COCCO5)=N1

Keywords:	9-(2-cyclopropylethynyl)-2-[(2S)-1,4-dioxan-2-ylmethoxy]-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one
Supplier:	Cayman Chemical
Supplier-Nr:	33185

Properties

Application:	GPR84 antagonist
MW:	378.4 D
Formula:	C22H22N2O4
Purity:	>95%
Format:	Solid

Database Information

CAS :	1445847-37-9\| Matching products
KEGG ID :	K08421 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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