Ginkgoneolic Acid

Ginkgoneolic acid is an anacardic acid and analog of anacardic acid monoene (Cay-18422) originally isolated from G. biloba and has diverse biological activities. It inhibits glycerol-3-phosphate dehydrogenase (GPDH, IC50 = 3 µg/ml). Ginkgoneolic acid inhibits PI3Kdelta (IC50 = 2.49 µM) and IgE-mediated RBL-2H3 mast cell degranulation in vitro (IC50 = 2.4 µM). It reduces S. mutans biofilm formation with a 50% biofilm inhibition concentration (MBIC50) value of 4 µg/ml.Formal Name: 2-hydroxy-6-tridecyl-benzoic acid. CAS Number: 20261-38-5. Synonyms: Anacardic Acid A, Ginkgolic Acid C13:0. Molecular Formula: C20H32O3. Formula Weight: 320.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 25 mg/ml. SMILES: OC1=CC=CC(CCCCCCCCCCCCC)=C1C(O)=O. InChi Code: InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-15-13-16-18(21)19(17)20(22)23/h13,15-16,21H,2-12,14H2,1H3,(H,22,23). InChi Key: VEPUCZUJLKAVNM-UHFFFAOYSA-N. Origin: Plant/Ginkgo biloba.