GeA-69

GeA-69 is an inhibitor of poly(ADP-ribose) polymerase 14 macrodomain 2 (PARP14 MD2). It binds to PARP14 MD2 (Kd = 860 nM) and inhibits PARP14 MD2 relocalization to the sites of DNA damage in U2OS cells when used at a concentration of 50 µM.Formal Name: N-[2-(9H-carbazol-1-yl)phenyl]-acetamide. CAS Number: 2143475-98-1. Molecular Formula: C20H16N2O. Formula Weight: 300.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Methanol: Soluble. SMILES: CC(NC1=C(C2=C3NC4=C(C=CC=C4)C3=CC=C2)C=CC=C1)=O. InChi Code: InChI=1S/C20H16N2O/c1-13(23)21-18-11-4-2-7-14(18)16-9-6-10-17-15-8-3-5-12-19(15)22-20(16)17/h2-12,22H,1H3,(H,21,23). InChi Key: LDPDVNYCIOHPGF-UHFFFAOYSA-N.