gamma-Terpinene

gamma-Terpinene is a monoterpene that has been found in various plants, including C. sativa, with diverse biological activities. It scavenges 2,2'-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS+) free radicals (IC50s = 2.8 and 30 mM, respectively) and reduces hemolysis induced by AAPH (Cay-82235) in isolated human erythrocytes. gamma-Terpinene reduces the growth of T. evansi in a concentration-dependent manner. It increases membrane permeability and decreases growth of X. oryzae bacteria. In vivo, gamma-terpinene (100 mg/kg) reduces Triton WR1339-induced increases in serum cholesterol and triglyceride levels in rats. It reduces paw edema induced by histamine, bradykinin (Cay-37408), carrageenan, and prostaglandin E2 (PGE2, Cay-14010) in mice. It also inhibits fluid extravasation in a mouse model of acetic acid microvascular permeability and reduces neutrophil migration in lung in a mouse model of acute lung injury.Formal Name: 1-methyl-4-(1-methylethyl)-1,4-cyclohexadiene. CAS Number: 99-85-4. Synonyms: NSC 21448. Molecular Formula: C10H16. Formula Weight: 136.2. Purity: >98%. Formulation: (Request formulation change), A neat oil. SMILES: CC1=CCC(C(C)C)=CC1. InChi Code: InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,7-8H,5-6H2,1-3H3. InChi Key: YKFLAYDHMOASIY-UHFFFAOYSA-N.