FM(TM)1-43

A styryl dye and an inhibitor of mechanosensitive ion channels, reversibly binds to cell membranes and has been used to monitor synaptogenesis and reinnervation, endocytosis, and vacuole formation in vitro, inhibits rapidly and slowly adapting mechanically activated currents in both capsaicin-insensitive and capsaicin-sensitive isolated rat dorsal root ganglion neurons from 0.6-15 µM, ex/em = 485/535 nm, respectively. Formulation: A solid. InChI: InChI=1S/C30H49N3.2BrH/c1-6-11-23-32(24-12-7-2)30-18-16-28(17-19-30)14-15-29-20-25-31(26-21-29)22-13-27-33(8-3,9-4)10-5,,/h14-21,25-26H,6-13,22-24,27H2,1-5H3,2*1H/q+2,,/p-2. InChIKey: VZUVCAGXYLMFEC-UHFFFAOYSA-L. SMILES: CC[N+](CC)(CC)CCC[N+](C=C1)=CC=C1C=CC2=CC=C(N(CCCC)CCCC)C=C2.[Br-].[Br-]