Fluticasone propionate

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
CDX-F0325-M005	5 mg		-	-	3 - 9 business days*		68.00€
CDX-F0325-M025	25 mg		-	-	3 - 9 business days*		206.00€

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White powder. Soluble in DMSO (20mg/ml) or DMF (20mg/ml). Chemical. CAS: 80474-14-2. Formula:... more

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Product information "Fluticasone propionate"

White powder. Soluble in DMSO (20mg/ml) or DMF (20mg/ml). Chemical. CAS: 80474-14-2. Formula: C25H31F3O5S. MW: 500.57. Fluticasone propionate is a synthetic corticosteroid. It is a high affinity, selective glucocorticoid receptor agonist (Kd = 0.5nM). It is used as an anti-inflammatory agent for asthma. It has low systemic bioavailability and has been investigated for effectiveness as an inhaled or intranasal corticosteroid to reduce airflow obstruction related to asthma, allergic rhinitis and other airway diseases. It potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis in vitro. It also potentiates KV1 channels (EC50 = 37nM).

Keywords:	Fluticasone 17-Propionate, (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester, CCI 18781
Supplier:	Chemodex
Supplier-Nr:	F0325