Flindokalner

Item number	Size	Delivery time	Price
TGM-T15286-1mg	1 mg	7 - 10 business days*	33.00€
TGM-T15286-5mg	5 mg	7 - 10 business days*	77.00€
TGM-T15286-1mL	1 ml	7 - 10 business days*	86.00€
TGM-T15286-10mg	10 mg	7 - 10 business days*	112.00€
TGM-T15286-25mg	25 mg	7 - 10 business days*	237.00€
TGM-T15286-50mg	50 mg	7 - 10 business days*	353.00€
TGM-T15286-100mg	100 mg	7 - 10 business days*	506.00€

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Description: Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator... more

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Product information "Flindokalner"

Description: Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. It is also a positive modulator of large conductance calcium-activated K channels (BKca) and displays negative modulatory activity at Kv7.1 channels (Ki = 3.7 µM). Additionally, Flindokalner acts as a negative modulator of GABAA receptors and demonstrates anxiolytic efficacy in vivo. Target: Potassium Channel. Smiles: COc1ccc(Cl)cc1[C@]1(F)C(=O)Nc2cc(ccc12)C(F)(F)F. References: Korsgaard MP, et al. Anxiolytic effects of Maxipost (BMS-204352) and retigabine via activation of neuronal Kv7channels. J Pharmacol Exp Ther. 2005 Jul,314(1):282-92.

Keywords:	BMS-204352
Supplier:	TargetMol
Supplier-Nr:	T15286

Properties

Application:	Targets potassium large conductance calcium-activated channel subfamily M beta member 1 (KCNMB1)
MW:	359.7 D
Formula:	C16H10ClF4NO2
Format:	32160405