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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CDX-F0337-M005 | 5 mg | - | - |
3 - 9 business days* |
61.00€
|
||
CDX-F0337-M025 | 25 mg | - | - |
3 - 9 business days* |
183.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
White to beige powder. Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (10mg/ml) Chemical.... more
Product information "Flibanserin"
White to beige powder. Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (10mg/ml) Chemical. CAS: 167933-07-5. Formula: C20H21F3N4O. MW: 390.4. Synthetic. Flibanserin is a full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A (Ki=1nm and 49nM, respectively). It also binds to dopamine D4 receptors with Ki values ranging from 4-24nM, but demonstrates no affinity for the other 5-HT subtypes or other neurotransmitter receptors. Multifunctional serotonergic ligands like flibanserin that can enhance downstream release of dopamine and norepinephrine while concomitantly reducing serotonin release in the brain circuits that mediate symptoms of reduced sexual interest and desire, are being studied clinically for therapeutic potential to improve sexual functioning. Flibanserin was investigated as a novel, non-hormonal treatment for pre-menopausal women with Hypoactive Sexual Desire Disorder (HSDD). Flibanserin was also found to reduce L-DOPA-induced dyskinesia in a model of Parkinson's Disease.
Keywords: | 1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one, BIMT 17, BIMT 17BS |
Supplier: | Chemodex |
Supplier-Nr: | F0337 |
Properties
Host: | Synthetic |
MW: | 390,4 D |
Formula: | C20H21F3N4O |
Purity: | >98% (HPLC) |
Format: | Solid |
Database Information
CAS : | 167933-07-5| Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H301, H315, H319, H335 |
P Phrases: | P261, P301+310, P305+351+338 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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