Fingolimod hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine... more
Product information "Fingolimod hydrochloride"
Description: Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells). Target: S1P Receptor, TRP/TRPV Channel, PAK, LPL Receptor. Smiles: Cl.CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1. References: Rolin J, et al. FTY720 and SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release. Cancer Immunol Immunother. 2010, 59(4), 575-586.
| Keywords: | Fingolimod (FTY720) HCl, FTY720 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2539 |
Properties
| Application: | Targets sphingosine 1-phosphate receptor 1 (S1PR1, EDG1, CD363) |
| MW: | 343.93 D |
| Formula: | C19H34ClNO2 |
Database Information
| CAS : | 162359-56-0| Matching products |
| KEGG ID : | K04288 | Matching products |
| Protein Atlas Nr. : | GPCR Modulators/A(nta)gonists |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335, H412 |
| P Phrases: | P261, P264, P271, P273, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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