Fenoxycarb

Fenoxycarb is a non-neurotoxic carbamate insecticide that acts as an insect growth regulator via juvenile hormone-like activity. It inhibits terminal development of first instar and newly transformed second instar nymphs of Florida red scale (C. aonidum) when used at a concentration of 0.0125% AI. Fenoxycarb (5 and 10 mg AI/colony) reduces the colony size index of laboratory colonies of red imported fire ants (S. invicta) by 93.6 to 95.9% at 8 weeks post-treatment. It is toxic to D. magna (LC50 = 0.5 mg a.s./L) and fish including O. mykiss, L. macrochirus, C. carpio, I. punctatus, and C. variegatus (LC50s = 0.66-1.5 mg a.s./L), but is not toxic to rats (LD50 = >10,000 mg/kg). Fenoxycarb is also an antagonist of alpha4beta40-, alpha4beta2-, alpha3beta4-, and alpha3beta2-containing rat nicotinic acetylcholine receptors (nAChRs, IC50s = 3, 2.4, 1.8, and 7.6 µM, respectively) but not rat brain acetylcholinesterase (AChE, IC50 = >1,000 µM).Formal Name: N-[2-(4-phenoxyphenoxy)ethyl]-carbamic acid, ethyl ester. CAS Number: 72490-01-8. Synonyms: ABG 6215, Ro 13-5223. Molecular Formula: C17H19NO4. Formula Weight: 301.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly soluble, Methanol: Slightly soluble. SMILES: O=C(OCC)NCCOC(C=C1)=CC=C1OC2=CC=CC=C2. InChi Code: InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19). InChi Key: HJUFTIJOISQSKQ-UHFFFAOYSA-N.