Fenbufen

Fenbufen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay28851-1 1 g -

6 - 10 business days*

44.00€
Cay28851-5 5 g -

6 - 10 business days*

128.00€
Cay28851-10 10 g -

6 - 10 business days*

231.00€
Cay28851-25 25 g -

6 - 10 business days*

521.00€
 
Fenbufen is a non-steroidal anti-inflammatory drug (NSAID) and a prodrug form of 4-biphenylacetic... more
Product information "Fenbufen"
Fenbufen is a non-steroidal anti-inflammatory drug (NSAID) and a prodrug form of 4-biphenylacetic acid. Fenbufen (125 µg/ml) inhibits collagen-induced, but not arachidonate-induced, platelet aggregation in vitro. In vivo, fenbufen (8-250 mg/kg) suppresses UV-induced erythema in guinea pigs. It reduces phenylquinone-induced writhing in mice (ED50 = 7.7 mg/kg) and brewer's yeast-induced mechano-allodynia in rats (ED50 = 29 mg/kg). Fenbufen (28 mg/kg) reduces inflammation in a rat model of adjuvant-induced arthritis. It also reduces yeast-induced fever in rats. Formulations containing fenbufen were previously used in the treatment of osteoarthritis and inflammatory pain.Formal Name: gamma-oxo-[1,1'-biphenyl]-4-butanoic acid. CAS Number: 36330-85-5. Synonyms: CL 82204. Molecular Formula: C16H14O3. Formula Weight: 254.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:20): 50µg/ml, Ethanol: 200 µg/ml. lambdamax: 282 nm. SMILES: O=C(CCC(O)=O)C(C=C1)=CC=C1C2=CC=CC=C2. InChi Code: InChI=1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19). InChi Key: ZPAKPRAICRBAOD-UHFFFAOYSA-N.
Keywords: CL 82204, gamma-oxo-[1,1'-biphenyl]-4-butanoic acid
Supplier: Cayman Chemical
Supplier-Nr: 28851

Properties

Application: COX inhibitor
MW: 254.3 D
Formula: C16H14O3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 36330-85-5| Matching products
KEGG ID : K11987 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301
P Phrases: P264, P270, P321, P330, P301+P310, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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