Ethionamide-d3

Ethionamide-d3 is intended for use as an internal standard for the quantification of ethionamide (Cay-23714) by GC- or LC-MS. Ethionamide is an antimycobacterial compound that is active against M. tuberculosis (MICs = 0.3-1.25 µg/ml). It is activated via oxidation by flavin monooxygenase and inhibits the InhA enzyme involved in mycolic acid biosynthesis. Formulations containing ethionamide have been used in the second-line treatment of multi-drug resistant tuberculosis.Formal Name: 2-ethyl-2,2,2-d3-4-pyridinecarbothioamide. CAS Number: 2748267-66-3. Molecular Formula: C8H7D3N2S. Formula Weight: 169.3. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Methanol: soluble. SMILES: NC(C1=CC=NC(CC([2H])([2H])[2H])=C1)=S. InChi Code: InChI=1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11)/i1D3. InChi Key: AEOCXXJPGCBFJA-FIBGUPNXSA-N.