Engeletin

Description: 1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 µg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM). Target: NF-kappaB, Reductase. Smiles: C[C@@H]1O[C@@H](O[C@@H]2[C@H](Oc3cc(O)cc(O)c3C2=O)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O. References: Huang H , Cheng Z , Shi H , et al. Isolation and Characterization of Two Flavonoids, Engeletin and Astilbin, from the Leaves of Engelhardia roxburghiana and Their Potential Anti-inflammatory Properties[J]. Journal of Agricultural and Food Chemistry, 2011, 59(9):4562-4569.