Endothall

Endothall is an aquatic plant growth regulator. It reduces curly leaf pondweed appearance frequency and dry biomass in lakes when applied annually at a concentration of 1 mg/L. Endothall reduces leaf chlorophyll content in A. thaliana plants and root length in A. thaliana seedlings (IC50s = 1.36 mM and 13.9 µM, respectively) and decreases duckweed growth rate (IC50 = 10 µM). It induces production of ethylene in bean leaves when applied at a concentration of 1 µM. Endothall is also an inhibitor of protein phosphatase 2A (PP2A, IC50 = 19-50 nM). It is toxic to mice (LD50 = 5-50 mg/kg). Formulations containing endothall have been used in the control of plants in aquatic environments.Formal Name: 7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid. CAS Number: 145-73-3. Synonyms: Endothal Acid, NSC 112771. Molecular Formula: C8H10O5. Formula Weight: 186.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 15 mg/ml, DMSO: 15 mg/ml, Ethanol: 15 mg/ml, PBS (pH 7.2): 0.2 mg/ml. SMILES: OC(C1C(C(O)=O)C2CCC1O2)=O. InChi Code: InChI=1S/C8H10O5/c9-7(10)5-3-1-2-4(13-3)6(5)8(11)12/h3-6H,1-2H2,(H,9,10)(H,11,12). InChi Key: GXEKYRXVRROBEV-UHFFFAOYSA-N.