Domiphen (bromide)

Domiphen is a quaternary ammonium-containing cationic surfactant with antimicrobial activity. It is active against A. viscosus, A. naeslundii, S. mutans, E. coli, and L. monocytogenes bacteria and inhibits C. neoformans yeast growth and spore germination. It also inhibits the human-ether-a-go-go-related gene (hERG) channel (IC50 = 1.5 µM in a whole-cell patch-clamp assay). Formulations containing domiphen have been used as antiseptics, disinfectants, and biocides in industrial, agricultural, veterinary, and clinical applications.Formal Name: N,N-dimethyl-N-(2-phenoxyethyl)-1-dodecanaminium, monobromide. CAS Number: 538-71-6. Synonyms: NSC 39415. Molecular Formula: C22H40NO . Br. Formula Weight: 414.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: soluble, Methanol: soluble, Water: soluble. lambdamax: 269 nm. SMILES: C[N+](CCCCCCCCCCCC)(C)CCOC1=CC=CC=C1.[Br-]. InChi Code: InChI=1S/C22H40NO.BrH/c1-4-5-6-7-8-9-10-11-12-16-19-23(2,3)20-21-24-22-17-14-13-15-18-22,/h13-15,17-18H,4-12,16,19-21H2,1-3H3,1H/q+1,/p-1. InChi Key: OJIYIVCMRYCWSE-UHFFFAOYSA-M.